Description

The Oncogenomics Section of the NCI Center for Cancer Research is seeking a postdoctoral fellow to join
a multidisciplinary translational research program focused on developing immune therapies for pediatric
cancers.
The fellow will generate and analyze data from Ewing sarcoma tumors using short- and long-read RNA
sequencing, immunopeptidomics, immune profiling, bioinformatics, and antigen discovery pipelines. The
project will prioritize EWSR1::FLI1/ERG, PRAME, and non-canonical epitopes in collaboration with CCR
cores and Johns Hopkins partners to develop TCR-based therapies for pediatric cancer.
Responsibilities include generating peptide-specific T cells, cloning and characterizing TCRs, defining
MHC restriction, and optimizing TCRs using single-cell sequencing, immunogenomics, spatial
transcriptomics, proteomics, and functional assays.

Candidates should be recent graduates (within 3 years) with a PhD, MD, or equivalent degree in
immunology, molecular biology, cell biology, or a related field. Hands-on experience in
immunogenomics, immunotherapy, immunology, adoptive cell therapy, gene therapy, and genome
editing is required.
If interested, please email me the following documents:
-Cover Letter
-Resume
-Contact Info of three professional references

Requirements

Candidates should be recent graduates (within 3 years) with a PhD, MD, or equivalent degree in
immunology, molecular biology, cell biology, or a related field. Hands-on experience in
immunogenomics, immunotherapy, immunology, adop..ve cell therapy, gene therapy, and genome
editing is required.